Prescription pitfalls: Medication use and driving risks in older adults

Examining over a decade of motor vehicle crash data involving older drivers, Brown study sheds light on a worrying trend: an increase in the prescription of potentially impairing medications, post-accident.

Many medications that older adults take can significantly impair their ability to drive a vehicle safely. But little is known about how potentially driving-impairing medications are prescribed to older populations specifically before and after motor vehicle crashes. Recognizing this knowledge gap, a team of researchers from the Brown University School of Public Health and the Center for Injury Research and Prevention at the Children’s Hospital of Philadelphia conducted a study, published in the Journal of the American Geriatrics Society, that investigated the types of medications older adults are using before accidents, and the changes made in medication regimens post-crash. 

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Lead Researcher Melissa Riester

The research team – led by Melissa Riester, research scientist at Brown’s Center for Gerontology and Healthcare Research, and Andrew Zullo, associate professor of epidemiology and of health services, policy and practice at the Brown University School of Public Health – examined data from people aged 67 or older, covered by Medicare in New Jersey, who were drivers involved in police-reported crashes between 2008 and 2017.

They focused on 36 types of medications known to potentially impair driving, analyzing their usage 120 days before and after each crash. Specifically, they tracked alterations in medication intake – both commencement and cessation – following the incidents.

“Use of one medication could increase the risk of a motor vehicle crash, and taking multiple medications together could further increase the risk,” Riester said. “However, few studies have examined how often individuals take multiple medications and how the number of these medications changes following a crash.”

“ Many older adults involved in crashes were already on multiple medications potentially impacting their driving abilities, and yet, post-crash, the prevalence of these medications tended to increase rather than decrease. ”

Here’s what they found: Among the 124,954 motor vehicle crashes involving individuals in the study, medications for most, 64%, were unchanged; 16% saw a decrease in medication while over 20% were prescribed an increased number of potentially impairing medications after the crash.

The study exposes a concerning pattern: many older adults involved in crashes were already on multiple medications potentially impacting their driving abilities, and yet, post-crash, the prevalence of these medications tended to increase rather than decrease.

This prompts a need to understand why medical practitioners often do not discontinue potentially driver-impairing medications following an auto accident, hinting at gaps in post-accident care and medication management for older adults.

Opioids, antihistamines, and antihypertensive drugs were frequently discontinued post-crash (6.2%, 2.1% and 1.7% of cases, respectively). Conversely, the most commonly initiated medications post-crash were opioids (8.3%), skeletal muscle relaxants (2.2%) and benzodiazepines (2.1%), which are used to treat anxiety disorders, insomnia and seizures, but are also likely to impair driving ability.

“Doctors might hesitate to stop medications that could affect driving abilities after a car accident because there aren’t clear guidelines on how to handle medications for older adults dealing with driving issues or accidents, especially if they’re taking multiple medications that could impair driving,” Riester said. 

Reister believes additional research could look even closer, connecting specific medications, and combinations of medications, to impaired driving in older adults.