Date June 25, 2026

Climate change could reshape flu seasons across the Americas, study finds

Researchers find that weather and climate patterns can help predict the timing and severity of flu outbreaks across diverse regions, and that flu spreads more easily in very dry and very humid air.

A new study led by researchers at the Brown University School of Public Health finds that weather conditions such as temperature and humidity can help predict when flu outbreaks occur and how severe they will become across North, Central and South America.

The findings, published in PNAS Nexus, suggest how climate change could reshape future flu seasons, with some tropical regions potentially experiencing stronger outbreaks while places with distinct seasons and colder winters could see somewhat smaller outbreaks.

“Investigating how climate affects influenza transmission across different locations is crucial for predicting outbreaks in the present, and in the future as the climate changes,” said first author Aleksandra Stamper, a Ph.D. candidate in Epidemiology at Brown University. “By understanding transmission as a function of humidity and temperature, we can reliably predict how the seasonal influenza outbreak in a state like Wisconsin will differ from the seasonal outbreak in Costa Rica.”

Seasonal influenza infects an estimated 1 billion people worldwide each year and causes hundreds of thousands of deaths. In much of the U.S., Canada and southern South America, where winters are colder, flu activity is typically concentrated and at its peak in the winter months. In tropical regions, influenza often circulates year-round and may produce two periods of heightened activity rather than a single, distinct flu season.

Scientists have long known that climate plays a role in influenza transmission, but it has remained unclear whether the same climate factors could explain outbreak patterns across both tropical and colder regions.

The new study helps provide that framework, identifying a common climate pattern linking temperature, humidity and influenza transmission. The pattern helps explain flu activity from colder regions to the tropics and provides a way to explore how future flu seasons may flip what’s typical as the climate warms.

“These same underlying climate relationships can explain very different observed outbreak patterns across latitudes,” said senior author Rachel Baker, assistant professor of epidemiology and of environment and society at Brown University. “In places with colder winters, low humidity and cooler temperatures drive intense winter outbreaks, while in tropical regions, warmer and more humid conditions can support flu activity over longer periods of time or even lead to two outbreaks in a year.”

For the study, the research team analyzed influenza data from 81 locations across North, Central and South America, spanning tropical, subtropical, and regions with colder winters. They combined that data with local temperature and humidity measurements and used an epidemiological model to examine how climate influences influenza transmission.

One surprising finding was that flu appeared to spread more easily when the air is either very dry or very humid, which may help explain why flu surges during cold, dry winters in places like the U.S. but can also spike during rainy seasons in some tropical regions.

“ Investigating how climate affects influenza transmission across different locations is crucial for predicting outbreaks in the present, and in the future as the climate changes. ”

Aleksandra Stamper Ph.D. candidate in Epidemiology

The researchers also used projections from 10 global climate models to explore how climate change could affect influenza outbreaks by the end of the century, finding that many regions with colder winters across the Americas may experience somewhat milder flu seasons in the future, while some tropical regions could see stronger outbreaks or changes in when flu activity peaks.

In the paper, the researchers note that climate is only one factor that influences influenza outbreaks. Vaccination rates, viral evolution, population density and human behavior also affect how the virus spreads.

Still, a better understanding of the link between climate and influenza could help improve disease forecasting and public health planning, they said.

“We don’t simply expect outbreak intensity to decrease everywhere under future climate conditions,” Stamper said. “But these projected changes reflect the complex relationship between climate and influenza transmission.”

This research was supported by the NASA Rhode Island Space Grant Consortium, the Burroughs Wellcome Fund, the National Institutes of Health’s National Institute of General Medical Sciences and the Government of Canada’s New Frontiers in Research Fund.